You might consider the difference between general knowledge about the world and self knowledge. Self knowledge refers to an individual's ability to accurately assess one's own strengths or weaknesses, emotional or mental states, ethical or moral behavior, etc. If you look at Act One, scene 2, you'll find that Edmund reveals something about self knowledge as he describes his own character. This might also give you some idea about how Edmund's own character could play a more important role in his downfall than Goneril or Regan.
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